[REVIEW] Kose Sekkisei Medicated Lotion | Before & After Pics

Kose Sekkisei Medicated Lotion Review:

The first time I discovered the Kose Sekkisei Medicated Lotion was around 2011, when I saw Taiwanese actress Ariel Lin endorsing the products in her drama “In Time With You”.

I was still a teenager back then and I remember being intrigued by that product in a beautiful sapphire blue jar. After looking at the price tag online I gave up, but I swore one day I would get to try this luxury beauty product by myself.

Well, fast forward a few years, I finally tried it, and here’s my review on it.


+ A lotion that offers clear, snow-white, fine-grained skin that is both moist and translucent. Trusted and adored by legions of fans since 1985.

+ A medicated cosmetic lotion with moisturizing oriental herbal extracts (coix seed, angelica, melothria).

+ Provides the skin with moisture and regulates the grain of dry skin. Prevents dullness that comes from dryness and makes the skin look translucent.

+ The watery texture gives a cooling and refreshing sensation

+ Weakly acidic.


Glycyrrhizinate Dipotassium*, Purified Water, Ethanol, Glycerin, Wheat Germ Oil, Angelica Acutiloba Root Extract, Coix Lacryma-Jobi Extract, Witch Hazel Extract, Melothria Heterophylla Extract, Tocopheryl Acetate, Citric Acid, Sodium Citrate, Sorbitan Sesquioleate, Glyceryl Tri-2-Ethylhexanoate, Octinoxate, Di-C12-15 Pareth-8 Phosphate, Polysorbate 80, Anhydrous Ethanol, Paraben, Fragrance.

*Active Ingredient

Kose Sekkisei Medicated Lotion Review

Volume: 200ml, 360ml.

How to use:

1. Use after wash.

2. Pour lotion generously onto a cotton pad and pat gently on face.

My Skin Type:

Combination: oily and dehydrated. I’m also acne prone and have sensitivities to certain ingredients.

Kose Sekkisei Medicated Lotion Review:

Let’s answer some questions first:

What does “medicated” mean?

In Japan beauty products are divided in quasi-drugs and cosmetics.
Quasi-drugs are products that due to their active ingredients have mild effects on the body. Cosmetic products that are considered quasi-drugs in Japan are labeled as “Medicated”.

What is the difference between the Kose Sekkisei Medicated Lotion and the Kose Sekkisei Lotion?

The Medicated Lotion is the original Japanese product. Like I mentioned before, cosmetics that are quasi-drugs in Japan must be labelled as Medicated. But since this is not mandatory in other countries, the export version of the lotion is only labeled as Sekkisei Lotion.

So, if you find the Sekkisei Lotion outside of Japan they are essentially the same product, although the ingredients may vary a bit from the Japanese version.

Now let’s take a look at the ingredients.

The active ingredient in this product is Dipotassium Glycyrrhizinate, which is a widely used anti-inflammatory component derived from the licorice root. It is reported to minimize redness in skin and to have some brightening effects.

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Other notable ingredients are Angelica Acutiloba Root Extract, Melothria Heterophylla Root Extract and Coix lacryma-jobi.

Angelica Acutiloba, also known as Tōki, is one of the most popular herbal medicines used in Asian countries, including Korea, China, and Japan. In medical studies it exhibits antioxidant and anti-allergic effects and it could serve as a potent anti-wrinkle agent. According to the Kosé website, it is expected to have hydrating effects.
Melothria heterophylla, popularly known as kundari, has also been shown to exhibit antioxidant effects.

Finally, Coix lacryma-jobi also known as Job’s tears or adlay, has shown its potential use as a skin whitening agent and could also act as a natural antioxidant. It is also a very popular and common ingredient in many Japanese cosmetic products.

Considering the claims and ingredients of this lotion, I started using it with the hope of seeing a brighter skin tone, as well as achieving that desired “glow” of a healthy, supple skin. I purchased a 24ml sample, that surprisingly lasted a few weeks even with daily use.

Kose Sekkisei Medicated Lotion Review

I consider this product a First Essence because of its active ingredients, so I apply it right after cleansing to let my skin soak up in all the extracts. I suspended the use of any other products that offer brightening effects with the purpose of testing if I could see any improvement in dark spots.

The product has a noticeable scent, a bit of alcohol and baby powder that dissipates once applied. It leaves my skin very soft and with a bouncy sensation. I didn’t experience any breakouts of eruptions, and my skin seemed very calm when I was using it. I also noticed a subtle glow to my skin.

Kose Sekkisei Medicated Lotion Review

As for the brightening effects, I believe the lightening of a few dark spots I had can be attributed to the lotion.
You can see in the before and after pictures the dark spots have slowly fade away, the pictures are taken about 3 weeks apart.

After finally trying out the lotion, I can say that I like it.

I like the subtle glow that brings to my skin, how bouncy and soft it leaves it. In my experience I can compare it to First Essences I’ve tried, like the Missha FTE, which gives me similar results for about the same price tag. I like the lotion, but I don’t love the price. I do appreciate the samples, though.

So will I repurchase it? Probably, I still want to try other products with similar ingredients, but I would like to come back to it some time again and see if I feel the same way about it.

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Where to buy:

Amazon | eBay | Yes Style

Have you tried Kose Sekkisei Medicated Lotion?

Do share your thoughts in comments.

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